Domestico graduated from Good Counsel Academy in White Plains and Nazareth College in Rochester.
She taught at Horton School and later worked for Strauss Paper Company, both in Port Chester.
She is survived by her son, Gregory, her daughter-in-law, Lea, and grandson Thomas.
Domestico was predeceased by her husband, Gary.
Visiting hours will be held on Sunday from 4 to 8 p.m. at Gunipero-Farenga Funeral Home, located at 353 Westchester Ave. in Port Chester.
A funeral Mass will be celebrated on Monday at 10:30 a.m. in Corpus Christi Church in Port Chester.
In lieu of flowers, donations can be made in her name to St. Jude Children's Foundation at www.stjude.org.
Online condolences can be posted at www.gffuneralhome.com.
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